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The role of dyslipidemia in diabetic retinopathy.

Citation
Hammer, S. S., and J. Busik V. “The Role Of Dyslipidemia In Diabetic Retinopathy.”. Vision Research, pp. 228-236.
Center University of Michigan
Author Sandra S Hammer, Julia Busik V
Keywords ASM, bone marrow, Cholesterol metabolism, Diabetic retinopathy, Dyslipidemia, Fatty acids, inflammation, Liver X receptor, miR-15a
Abstract

Diabetic retinopathy (DR) affects over 93million people worldwide and is the number one cause of blindness among working age adults. These indicators coupled with the projected rise of patients diagnosed with diabetes, makes DR a serious and prevalent vision threating disease. Data from recent clinical trials demonstrate that in addition to the well accepted role of hyperglycemia, dyslipidemia is an important, but often overlooked factor in the development of DR. The central aim of this review article is to showcase the critical role of dyslipidemia in DR progression as well as highlight novel therapeutic solutions that take advantage of the vital roles lipid metabolism plays in DR progression.

Year of Publication
2017
Journal
Vision research
Volume
139
Number of Pages
228-236
Date Published
12/2017
ISSN Number
1878-5646
DOI
10.1016/j.visres.2017.04.010
Alternate Journal
Vision Res.
PMID
28545981
PMCID
PMC5702582
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