Joslin Molecular Phenotyping and Genotyping Core

Overview

The objective of the Molecular Phenotyping and Genotyping Core is to support Joslin and external investigators in the study of molecular mechanisms of disease by providing equipment, expertise, and services in molecular phenotyping, including nucleic acid sequence analyses, gene expression, and other "-omics" analyses, which would be too specialized or costly for individual laboratories to perform independently.

Services

• DNA Extraction
• SNP genotyping
• DNA Purification
• Genetic assay for clinical studies
• Nucleic acid quantification
• MALDI Biotyper
• Tissue homogenization
• Real-time quantitative PCR expression analysis
• Digital PCR
• Seahorse Extracellular Flux Analysis
• Single cell/nucleus RNA sequencing
• Consultation and Training