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Matthew J Brady PhD

Matthew Brady, PhD, is an Associate Professor of Adult and Pediatric Endocrinology, Diabetes and Metabolism at the University of Chicago, and is Vice Chair of the Committee on Molecular Metabolism and Nutrition in the Biological Sciences Division. He also has been appointed to the Committee on Molecular Pathogenesis and Molecular Medicine and to the Committee on Cell Physiology. His research focuses on the relationship between metabolism, diabetes and lipid (fat) storage. The overall focus of his lab is metabolic signaling. Dr. Brady is particularly interested in the insulin-mediated regulation of energy storage in adipocytes and hepatocytes, the interplay of glucose and lipid metabolism, the regulation of hepatic glucose production, and the molecular mechanisms underlying the development of insulin resistance in animal models and humans. His research is conducted using cell lines, primary murine hepatocytes and adipocytes, and samples collected from human fat biopsies.

Dr. Brady has served as a reviewer for 17 medical journals including Diabetes, the Journal of Biochemistry and Obesity Research. He has published more than 45 research articles in peer-reviewed journals and has presented seminars at universities and medical institutions worldwide. Dr. Brady also has served on numerous grant review panels for the National Institutes of Health. Among his current research are projects focused on hormonal regulation of energy metabolism and the effects of modulating sleep patterns on insulin Sensitivity in human adipose tissue.