Albert Einstein College of Medicine

The Einstein-Mount Sinai Diabetes Research Center (ES-DRC) comprises a vibrant, extensive, diverse, well-funded and highly productive program that provides the foundation for high-quality and cutting-edge research in diabetes and related studies in obesity, metabolism and endocrinology. The mission of the Einstein-Mount Sinai Diabetes Research Center (ES-DRC)—a joint project of Albert Einstein College of Medicine and Icahn School of Medicine at Mount Sinai—is to conduct basic, translational, behavioral, and clinical research into type 1 and type 2 diabetes and related metabolic conditions.

Areas of Research

Studies at ES-DRC fall into six major interrelated areas:

  • islet biology and immunology
  • signal transduction
  • central and peripheral regulation of metabolism
  • diabetic complications
  • metabolic patient-oriented research and diabetes-focused clinical trials
  • social-environmental determinants of metabolic health
Resources and Collaborations

The ES-DRC also includes:

  • Diabetes-specific core facilities
  • The Pilot and Feasibility Study program, which fosters new diabetes-related research by faculty at Einstein, Mt. Sinai, and other participating institutions, and an enrichment program designed to initiate research programs in biomedical and behavioral diabetes-related areas
  • The Montefiore-Einstein Clinical Diabetes Center
  • The Global Diabetes Institute
  • The Mount Sinai Diabetes and Obesity Metabolism Institute
  • The Mount Sinai Clinical Diabetes Center
Collaborations

All told, ES-DRC comprises more than 100 independent laboratories—a scientific base that serves as resource for diabetes investigators nationwide. Our researchers collaborate with investigators at New York University, Weill Cornell Medical College, Cornell University, New York Medical College, Winthrop University Hospital, Stony Brook University, and Hunter College.

Support

In additional to the National Institutes of Health, ES-DRC interacts with and provides collaborative research support to the New York Obesity Research Center and the Center for the Study of Diabetic Complications.

Partner Institutions

Icahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai

Research Cores

Animal Physiology & Phenotyping
Einstein Animal Physiology Core Gary J Schwartz PhD
The Einstein Animal Physiology Core assists biomedical investigators in the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats.
Clinical & Translational Studies
Einstein Translational Research CoreJill P Crandall MD
The primary mission of the Einstein Translational Research Core is to promote high-quality diabetes translational research, through delivery of services including consultation, technical support, training and mentoring that are specifically applicable to diabetes.
Histology, Morphology & Imaging
Einstein Immuno-Technology CoreTeresa P DiLorenzo PhD
The new Immuno-Technology Core (ITC) has been conceived as an education, coordination and service core that offers access to advanced cellular, imaging and immunomodulation technology platforms operated across both Einstein and Mount Sinai.
Islet Biology & Metabolism
Einstein Human Islet and Adenovirus CoreAdolfo Garcia-Ocaña PhD
The Human Islet & Adenovirus Core provides key methodologies, technology and infrastructure to support investigators in the use of human islets for research studies for the Einstein-Mount Sinai Diabetes Research Center.
Protein, Proteomics, Metabolomics & Mass Spectrometry
Einstein Stable Isotope & Metabolomics Core Irwin J Kurland MD PhD
The newly established Einstein Stable Isotope and Metabolomics Core uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function.

Center People

Center Director
Jeffrey E Pessin Jeffrey E Pessin PhD Email
Core Director
Jill P Crandall MD Einstein Translational Research Core Email
Teresa P DiLorenzo PhD Einstein Immuno-Technology Core Email
Adolfo Garcia-Ocaña PhD Einstein Human Islet and Adenovirus Core Email
Irwin J Kurland MD PhD Einstein Stable Isotope & Metabolomics Core Email
Gary J Schwartz Gary J Schwartz PhD Einstein Animal Physiology Core Email
Pilot & Feasibility Director
Streamson C Chua Jr MD PhD Einstein Pilot & Feasibility Program Email