SF1 Neurons In The Physiology And Pathophysiology Of Glucose Control

The incidence and prevalence of diabetes continue to rise on a global scale. Increasing evidence suggests that in addition to peripheral mechanisms, the brain also has the capacity to regulate blood sugars. However, much about how the brain controls circulating glucose and the pathologies induced by its dysregulation remain unknown. The goal of this project is to investigate the mechanisms whereby this occurs and the specific neurons involved in mediating this effect.