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Diabetes Resources

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Diabetes Resource Description Resource Category RRID
Accelerating Medicines Partnership (AMP) The Accelerating Medicines Partnership (AMP) is a public-private partnership to transform the current model for developing new diagnostics and treatments by jointly identifying and validating promising biological targets for therapeutics. Data Repositories
Research Networks
Action for Health in Diabetes (Look AHEAD) Look AHEAD (Action For Health in Diabetes) is a multi-center randomized clinical trial to examine the effects of a lifestyle intervention designed to achieve and maintain weight loss over the long term through decreased caloric intake and exercise. Clinical Research SCR_001490
Action to Control Cardiovascular Disease Risk in Diabetes (ACCORD) This NHLBI study is testing whether strict glucose control lowers the risk of heart disease and stroke in adults with type 2 diabetes. Clinical Research SCR_009015
Acute Liver Failure Study Group (ALFSG) A Multi-Center Trial to Study Acute Liver Failure in Adults (AALF) is a prospective cohort study currently being conducted by the ALFSG. Clinical Research SCR_001463
Acute Renal Failure Trial Network (ATN) Study The Acute Renal Failure Trial Network (ATN) study was established to determine whether more intensive renal replacement therapy decreases mortality among critically ill patients with acute kidney injury. Clinical Research
Adult To Adult Living Donor Liver Donor Liver Transplantation Cohort Study (A2ALL) The primary goal of A2ALL is to provide valuable information on the outcomes of both potential and actual recipients and their donors who have been evaluated for adult-to-adult living donor liver transplantation. Clinical Research SCR_001494
African American Study of Kidney Disease and Hypertension (AASK) Clinical Trial and Cohort Study The AASK Cohort Study is an extension of the AASK Clinical Trial, which investigated the effects of blood pressure control and the use of specific drug regimens on the progression of chronic kidney disease in African Americans with hypertension. Clinical Research SCR_006985
Autoimmunity Centers of Excellence (ACEs) The centers that make up the ACE program conduct clinical trials and basic research on new immune-based therapies for autoimmune diseases. Clinical Research
Research Networks
Behavior Enhances Drug Reduction of Incontinence (BE-DRI) The Behavior Enhances Drug Reduction of Incontinence (BE-DRI) study was a multicenter, randomized clinical trial that combined behavioral training and pharmacological treatment with the goal of improving patient outcomes. Clinical Research SCR_001495
Boston Area Community Health (BACH) Survey The Boston Area Community Health (BACH) Survey was an epidemiologic study established by the NIDDK designed to estimate the prevalence of urologic symptoms and conditions by race/ethnicity, age, sex, and socioeconomic status. Clinical Research SCR_007115
Bridging Interventional Development Gaps (BrIDGs) The BrIDGs program assists researchers in advancing promising therapeutic agents through late-stage pre-clinical development toward an Investigational New Drug (IND) application and clinical testing. Clinical Research SCR_005635
Bypass Angioplasty Revascularization Investigation (BARI) 2 Diabetes The NHLBI-led BARI-2D study aims to determine the best therapies for people with type 2 diabetes and moderately severe cardiovascular disease. Clinical Research SCR_001496
C-peptide Standardization Clinical trials of agents to preserve beta cell function in new onset type 1 diabetes will use C-peptide as an outcome measure that indicates insulin production. Standardization SCR_001499
Center for Inherited Disease Research (CIDR) A centralized facility established to provide genotyping and statistical genetics services for investigators seeking to identify genes that contribute to human disease. Research Networks SCR_007339
Centers for Disease Control (CDC) Diabetes Health Resources for the Public CDC's Division of Diabetes Translation translates diabetes research into daily practice to understand the impact of the disease, influence health outcomes, and improve access to quality health care. Health Information
Central NIDDK Repository for Biosamples and Data The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) established Central NIDDK Repositories for biosamples and data collected in clinical studies. Data Repositories
Research Networks
Chronic Prostatitis Collaborative Research Network Clinical Trial- Alfuzosin The purpose of this randomized clinical trial is to evaluate the efficacy and safety of the alpha adrenergic blocker Alfuzosin (Uroxatral) in men with relatively new onset of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Clinical Research SCR_015886
Chronic Renal Insufficiency Cohort (CRIC) Study The objectives of CRIC are to improve understanding of the relationship between CKD and CVD and to examine traditional and non-traditional ("uremia-related")) risk factors for progression of CKD and CVD among patients with reduced kidney function. Clinical Research SCR_009016
CKID A Prospective Cohort Study of Kidney Disease in Children The CKiD Study is a NIH-funded, multicenter, prospective cohort study of children aged 6 months to 16 years with mild to moderate impaired kidney function. Clinical Research SCR_001500
Clinical Islet Transplantation Consortium (CIT) The Clinical Islet Transplantation (CIT) Consortium is a network of clinical centers and a data coordinating center conducting studies of islet transplantation in patients with type 1 diabetes. Clinical Research SCR_014385
Clinical Outcomes Research Initiative (CORI) The Clinical Outcomes Research Initiative, CORI, provides gastrointestinal physicians, nurses and researchers with software, research data and tailor-made services aimed to advance the overall practice of endoscopy. Clinical Research
Data Repositories
Clinical Trials in Organ Transplantation (CTOT) The Clinical Trials in Organ Transplantation (CTOT) project is an investigative consortium for conducting clinical and associated mechanistic studies that will lead to improved outcomes for transplant recipients. Clinical Research SCR_015859
Collaborative Islet Transplant Registry (CITR) The Collaborative Islet Transplant Registry's mission is to expedite progress and promote safety in islet/beta cell transplantation through the collection, analysis, and communication of comprehensive and current data on all islet/beta cell transplants. Clinical Research
Data Repositories
Common Metabolic Diseases Knowledge Portal (CMDKP) The Common Metabolic Diseases Knowledge Portal enables browsing, searching, and analysis of human genetic information linked to common metabolic diseases and traits, while protecting the integrity and confidentiality of the underlying data. Data Repositories
Research Networks
Cooperative Study Group for Autoimmune Disease Prevention The mission of the Autoimmune Disease Prevention Centers is to engage in scientific discovery which significantly advances knowledge for the prevention and regulation of autoimmune disease. Research Networks SCR_006803
Creatinine Standardization Program, Laboratory Professionals The NKDEP Laboratory Working Group has launched the Creatinine Standardization Program to address inter-laboratory variation in creatinine assay calibration and provide more accurate estimates of GFR. Standardization SCR_006441
Diabetes in America A compilation and assessment of epidemiologic, public health, and clinical data on diabetes and its complications in the United States. Data Repositories SCR_006754
Diabetes Prevention Trial--Type 1 (DPT-1) The Diabetes Prevention Type 1 (DPT-1) trial is a NIDDK-funded multi-center clinical trial to determine if treatment with beta-cell antigens can delay the onset of Type 1 Diabetes Mellitus in non-diabetic relatives of persons with Type 1 DM. Data Repositories SCR_001467
Diabetic Complications Consortium (DiaComp) The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to provide an environment that will foster communication and collaboration between investigator communities involved in complications research. Research Networks SCR_001415
Digestive Diseases The digestive diseases clearinghouse provides comprehensive information about digestive health and disease for the public: online, in booklets and fact sheets, by email, and over the phone. Data Repositories
Digestive Diseases Research Core Centers The Digestive Diseases Research Core Centers (DDRCCs) and Digestive Diseases Research Development Centers (DDRDCs) coordinate and foster interdisciplinary cooperation between groups of established investigators to advance digestive research. Research Networks SCR_015212
Digestive Diseases Statistics for the United States A collection of statistics about specific digestive diseases, including prevalence, mortality, care delivery and cost. Data Repositories SCR_006703
Drug Induced Liver Injury Network (DILIN) The purpose of the Drug-Induced Liver Injury Network (DILIN) is to collect and carefully analyze cases of liver problems caused by prescription drugs and alternative medicines, such as herbal products. Research Networks SCR_001524
Epidemiology of Diabetes Interventions and Complications (EDIC) An observational study examining the risk factors associated with the long-term complications of type 1 diabetes. The study began in 1994 and follows the 1441 participants previously enrolled in the Diabetes Control and Complications Trial (DCCT). Clinical Research
Data Repositories
Genetics of Kidneys in Diabetes Study (GoKinD) The fundamental aim of GoKinD is to facilitate investigator-driven research into the genetic basis of diabetic nephropathy by collecting, storing, and distributing genetic samples from cases and controls of type 1 diabetes and diabetic nephropathy. Clinical Research
Research Networks
Globin Gene Server This database provides data and tools for studying the function of DNA sequences, with an emphasis on those involved in the production of hemoglobin. Data Repositories SCR_001480
Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) is a long-term study of different treatments for type 2 diabetes. Clinical Research SCR_014384
Healthy People 2020 This interactive data tool allows users to explore data and technical information related to the Healthy People 2020 objectives. Data Repositories SCR_001446
Human Islet Research Network (HIRN) HIRN’s mission is to better understand how human beta cells are lost in Type 1 Diabetes and to find innovative strategies to protect or replace functional beta cell mass in diabetic patients. Research Networks SCR_014393
Human Pancreas Analysis Program (HPAP) Human Pancreas Analysis Program (HPAP) is performing deep phenotyping of the human endocrine pancreas and its interaction with the immune system, to better understand the cellular and molecular events that precede and lead to the beta cell loss in Type-1 Diabetes (T1D). The National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) supports HPAP through multiple NIH grants. Research Networks SCR_016202
Human Tissue and Organs for Research Resource (HTORR) NDRI’s HTORR Program provides academic biomedical investigators with donated normal and diseased human tissues and organs recovered from a diverse donor pool using customized procurement, processing, and preservation and distribution protocols. Data Repositories
Immune Tolerance Network (ITN) The ITN is an international consortium of scientists and physicians dedicated to the clinical evaluation of novel tolerogenic approaches for the treatment of autoimmune diseases, asthma and allergic diseases, and the prevention of graft rejection. Clinical Research
Research Networks
Immuno Polymorphism Database (IPD) IPD was developed in 2003 to provide a centralised system for the study of polymorphism in genes of the immune system. Data Repositories SCR_003004
ImmunoBase Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. Data Repositories SCR_014642
Immunology Database and Analysis Portal (ImmPort) ImmPort is a long-term, sustainable data warehouse for the purpose of promoting re-use of immunological data generated by NIAID DAIT and DMID funded investigators. ImmPort supports analysis of flow cytometry results and HLA genetic associations. Data Repositories SCR_012804
Inflammatory Bowel Disease Genetic Consortium (IBDGC) The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) consists of investigators from seven sites in the U.S. and Canada, who have recruited a large sample of inflammatory bowel disease patients, their relatives, and control subjects. Data Repositories SCR_001461
Integrated Islet Distribution Program (IIDP) The IIDP mission is to distribute high quality human islets to the diabetes research community, in order to advance scientific discoveries and translational medicine. Pivotal to IIDP’s mission is providing reliable, high quality resources to the research community from industry-leading Islet Isolation Centers (IICs). Research Networks SCR_014387
International Mouse Phenotyping Consortium (IMPC) The goal of the International Mouse Phenotyping Consortium (IMPC) is to discover functional insight for every gene by generating and systematically phenotyping 20,000 knockout mouse strains. Research Networks SCR_006158
Kidney Disease Statistics for the United States The UDA compendium delineates the changes in the epidemiology, health economic impact, and practice patterns for the diseases currently included within the scope of practice of the specialty of urology, analyzed retrospectively over a ten-year period. Data Repositories
Knockout Mouse Project Repository (KOMP) The Mutant Mouse Resource and Research Center (MMRRC) acquired the genetically-altered mice and embryonic stem (ES) cells made as part of the NIH Knockout Mouse Project (KOMP) and previously maintained in the KOMP Repository. The KOMP Repository collection at MMRRC will provide investigators with the convenience of a one-stop portal to one of the largest inventories of mutant mouse strains and ES cell lines available to the biomedical research community. Research Networks SCR_007318
Monogenic Diabetes Registry The Monogenic Diabetes Registry includes two types of monogenic diabetes research: MODY, commonly caused by mutations in the HNF1A gene or the GCK gene, and Neonatal diabetes, often caused by a mutation in any one of three genes: KCNJ11, ABCC8 or INS. Data Repositories SCR_015883
Mouse Metabolic Phenotyping Centers (MMPC) The MMPC provides standardized, high quality metabolic and physiologic phenotyping services for mouse models of diabetes, diabetic complications, obesity and related disorders. Research Networks SCR_008997
Mutant Mouse Regional Resource Centers (MMRRC) The MMRRC distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. Research Networks SCR_002953
National Diabetes Education Program (NDEP) The NDEP is the leading federal government public education program that promotes diabetes prevention and control. The mission of the NDEP is to reduce the morbidity and mortality associated with diabetes and its complications. Data Repositories SCR_001477
National Diabetes Information Clearinghouse (NDIC) The diabetes clearinghouse provides comprehensive information about diabetes for the public: online, in booklets and fact sheets, by email, and over the phone. Data Repositories SCR_006702
National Disease Research Interchange (NDRI) The mission of NDRI is to provide human biospecimens worldwide to advance biomedical/bioscience research and development and education in the life sciences. Data Repositories SCR_000550
National Gene Vector Biorepository (NGVB) The goals of the NGVB are to maintain a Pharm/Tox database, provide a reagent repository, biorepository and archiving services, educational material about gene therapy, IND-enabling testing services, and conduct research related to gene therapy safety. Clinical Research
Data Repositories
National Glycohemoglobin Standardization Program (NGSP) The purpose of the NGSP is to standardize Hemoglobin A1c test results to those of the Diabetes Control and Complications Trial (DCCT) and United Kingdom Prospective Diabetes Study (UKPDS). Standardization SCR_015885
National Kidney Diseases Education Program (NKDEP) The National Kidney Disease Education Program (NKDEP) aims to increase awareness of kidney disease and its risk factors, the importance of testing those at risk, and the availability of treatment to prevent or slow the progression to kidney failure. Data Repositories SCR_006527
Network for Pancreatic Organ Donors with Diabetes (nPOD) The goals of the nPOD initiative are to maintain a network of procuring and characterizing, in a collaborative manner, pancreata and related tissues from cadaveric organ donors with type 1 diabetes as well as those whom are islet autoantibody positive. Clinical Research SCR_014641
NIDDK Endocrine and Metabolic Diseases Information Service This public service provides information about endocrine and metabolic diseases in easy-to-understand language: online, in booklets and fact sheets, by email, and over the phone. Data Repositories
NIDDK Genetics Repository The Genetics Repository receives blood samples collected in many different studies, and processes them to create immortalized cell lines, and DNA samples. Data Repositories SCR_006542
NIDDK Health Information for the Public The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports basic and clinical research on many of the most serious diseases affecting public health. Health Information
NIDDK Hematologic Diseases Information Service This service provides information about certain hematologic diseases in easy-to-understand language: online, in booklets and fact sheets, by email, and over the phone. Data Repositories
NIDDK Information Network (dkNET) dkNET is a search portal and information hub that helps researchers find research resources and data repositories relevant to their research and keep up to date on new tools, services and mandates to support robust and reproducible science. Data Repositories
Research Networks
Non-human Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) The NHPCSG, a multi-institution consortium, was established to evaluate the safety and efficacy of novel donor-specific, tolerance induction therapies in non-human primate (NHP) models of kidney and islet transplantation. Research Networks SCR_006847
Nutrition Obesity Research Centers The Nutrition Obesity Research Centers offer state-of-the art technologies and resources to investigators who are pursuing studies in nutrition, obesity and other related research areas. Research Networks SCR_004131
Organ Procurement and Transplantation Network (OPTN) The U.S. Organ Procurement and Transplantation Network (OPTN) maintains a registry of human tissues in order to ensure the success and efficiency of the U.S. organ transplant system. Clinical Research
Data Repositories
Pediatric Acute Liver Failure Study Group (PALF) The PALF Study is the first multi-center, multi-national collaborative study aimed at identifying, characterizing, and developing management strategies for infants, children, and adolescents who present with acute liver failure. Data Repositories
Research Networks
Preventing Early Renal Loss in Diabetes (PERL) PERL is a clinical trial for people with type 1 diabetes who have early signs of kidney problems. Our goal is to test a new way to reduce loss of kidney function using a safe and inexpensive medicine. Clinical Research SCR_015862
ReBuilding a Kidney (Re)Building a Kidney is an NIDDK-funded consortium of research projects working to optimize approaches for the isolation, expansion, and differentiation of appropriate kidney cell types and their integration into complex structures that replicate human kidney function. Research Networks SCR_014442
Restoring Insulin Secretion study (RISE) The RISE Study is recruiting adults and children with early type 2 diabetes or who are at risk for type 2 diabetes. RISE includes 3 studies examining whether aggressive glucose lowering will lead to recovery of pancreas function. Clinical Research SCR_014383
T1D Exchange T1D Exchange is a nonprofit research organization dedicated to accelerating therapies and improving care for people living with type 1 diabetes. Data Repositories SCR_014532
TEDDY (The Environmental Determinants of Diabetes in the Young) The TEDDY consortium is looking for the causes of type 1 diabetes mellitus, including genetic and genetic-environmental interactions and childhood infections or other environmental factors predisposing to development of Type I Diabetes Mellitus. Clinical Research SCR_000383
The Childhood Liver Disease Research and Education Network (ChiLDREN) The ChiLDReN Network was developed to support the discovery of new diagnostics, etiologic, and treatment options for ChiLDReN with liver disease, and those who undergo liver transplantation. Clinical Research SCR_001497
Type 1 Diabetes TrialNet Type 1 Diabetes TrialNet is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes. Clinical Research SCR_001508
United States Renal Data System (USRDS) The United States Renal Data System (USRDS) is a national data system that collects, analyzes, and distributes information about chronic kidney disease and end-stage renal disease (ESRD) in the United States. Data Repositories SCR_006699