P&F Studies

2020
Pilot Awardee	Center	Pilot Study
Jason Spaeth PhD	Indiana University	Dynamic regulations of Pdx1 activity and beta cell function and identity through the Snd1 coregulator
Diana Stanescu MD	University of Pennsylvania	The role of SLC38A5 in pancreatic α cell development
Christoph Thaiss PhD	University of Pennsylvania	Microbiome-clock interactions in metabolic disease
Linus Tzu-Yen Tsai MD PhD	Joslin Diabetes Center	The role of interferon regulatory factors in tanycytes during HFD-induced inflammation, obesity and glucose dysregulation
Xiaoxiao Wan MD PhD	Washington University in St Louis	Explore the Immunosuppressive Effects of Monoclonal Insulin Autoantibodies in Type 1 Diabetes
Luke Wander MD MS	University of Washington	Identifying miRNA-Mediated Mechanisms Driving the Protective Effects of Metformin on Beta-Cell Function
Jessica Williams PhD	University of Alabama at Birmingham	Clinician Implicit Bias and Perceived Barriers to Medication Intensification: A Pilot & Feasibility Study
Jessica Wilson MD MS	University of Pennsylvania	Metabolic Phenotype and Type 2 Diabetes Polygenic Risk Score
Clyde Wright MD	University of Colorado Denver	Pathogenic Role of IκBβ/NFκB signaling in ER Stress Induced β-cell Injury and Death
Min Xie MD PhD	University of Alabama at Birmingham	HDAC Upregulation by Chronic Beta-Hydroybutyrate Exposure Exacerbates Ischemia/Reperfusion Injury During Diabetes Mellitus
Pingwen Xu PhD	University of Chicago	Preoptic anterior hypothalamus receptor-alpha controls energy homeostasis
Richard Zare, PhD	Stanford University	Development and Validation of an Enabling Methodology for Measuring Islet-Specific Drug Delivery in vivo

2019
Pilot Awardee		Center	Pilot Study
Amanda Ackermann MD PhD		University of Pennsylvania	Identifying Targets to Enhance Beta Cell Response in Diabetes using Single-Cell Functional Genomics
Eric Appel PhD		Stanford University	Expanding Global Access to Insulin by Eradicating the Cold Chain